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Gene : CRTC2 Homo sapiens

Name  ? CREB regulated transcription coactivator 2 Cytological Location  1q21.3
Brief Description  CREB regulated transcription coactivator 2
Description  This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010]
  • synonyms:
  • TORC2,
  • TORC2,
  • CRTC2,
  • NM_181715,
  • uc057leo.1,
  • OTTHUMG00000037156,
  • AY360172,
  • HGNC:27301,
  • TORC-2
  • identifiers:
  • 200186,
  • ENSG00000160741,
  • CRTC2

Genome feature

Region: gene ? Length: 10969  
Location: 1:153947675-153958643 reverse strand Cyto location: 1q21.3


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

3753 SN Ps

5 Cross References

15 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results