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Gene : HTRA4 Homo sapiens

Name  ? HtrA serine peptidase 4 Cytological Location  8p11.22
Brief Description  HtrA serine peptidase 4
Description  This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging. [provided by RefSeq, Oct 2008]
  • synonyms:
  • NM_153692,
  • HGNC:26909,
  • HTRA4,
  • AK075205,
  • uc003xmj.4,
  • OTTHUMG00000164070,
  • FLJ90724
  • identifiers:
  • 203100,
  • ENSG00000169495,
  • HTRA4

Genome feature

Region: gene ? Length: 14515  
Location: 8:38974149-38988663 Cyto location: 8p11.22


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

45 SN Ps

5 Cross References

14 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results