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Function
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96 Pathways
- Interleukin-4 and Interleukin-13 signaling,
- Cytokine Signaling in Immune system,
- RUNX2 regulates genes involved in cell migration,
- G beta:gamma signalling through PI3Kgamma,
- KSRP (KHSRP) binds and destabilizes mRNA,
- Costimulation by the CD28 family,
- Activation of BH3-only proteins,
- Signal Transduction,
- Metabolism of vitamins and cofactors,
- G-protein beta:gamma signalling,
- Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation,
- Signaling by ERBB2,
- Extra-nuclear estrogen signaling,
- Signaling by Interleukins,
- TP53 Regulates Metabolic Genes,
- Negative regulation of NOTCH4 signaling,
- Cyclin E associated events during G1/S transition ,
- VEGFA-VEGFR2 Pathway,
- Apoptosis,
- Cell Cycle,
- AKT-mediated inactivation of FOXO1A,
- CD28 co-stimulation,
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling,
- Intrinsic Pathway for Apoptosis,
- GPCR downstream signalling,
- Regulation of mRNA stability by proteins that bind AU-rich elements,
- Diseases of signal transduction by growth factor receptors and second messengers,
- Regulation of PTEN stability and activity,
- FOXO-mediated transcription,
- Immune System,
- ESR-mediated signaling,
- VEGFR2 mediated vascular permeability,
- Cell Cycle, Mitotic,
- G1/S Transition,
- Estrogen-dependent nuclear events downstream of ESR-membrane signaling,
- Signaling by NOTCH4,
- Activation of BAD and translocation to mitochondria ,
- Cyclin A:Cdk2-associated events at S phase entry,
- Metabolism,
- Vesicle-mediated transport,
- Intracellular signaling by second messengers,
- MTOR signalling,
- Downregulation of ERBB2:ERBB3 signaling,
- Regulation of beta-cell development,
- Transcriptional Regulation by TP53,
- Regulation of TP53 Expression and Degradation,
- Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA,
- S Phase,
- Gene expression (Transcription),
- AKT phosphorylates targets in the nucleus,
- Rab regulation of trafficking,
- Signaling by VEGF,
- Regulation of gene expression in beta cells,
- Signaling by Nuclear Receptors,
- Generic Transcription Pathway,
- Programmed Cell Death,
- Hemostasis,
- CTLA4 inhibitory signaling,
- Signaling by NOTCH,
- CD28 dependent PI3K/Akt signaling,
- Developmental Biology,
- Regulation of TP53 Activity through Acetylation,
- Metabolism of cofactors,
- PTEN Regulation,
- RAB GEFs exchange GTP for GDP on RABs,
- PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1,
- PI3K/AKT Signaling in Cancer,
- RNA Polymerase II Transcription,
- Regulation of TP53 Degradation,
- eNOS activation,
- Membrane Trafficking,
- Signaling by WNT,
- Platelet activation, signaling and aggregation,
- Signaling by Non-Receptor Tyrosine Kinases,
- TCF dependent signaling in response to WNT,
- Downregulation of ERBB2 signaling,
- Deactivation of the beta-catenin transactivating complex,
- Regulation of TP53 Activity,
- Platelet Aggregation (Plug Formation),
- Regulation of localization of FOXO transcription factors,
- AKT phosphorylates targets in the cytosol,
- Negative regulation of the PI3K/AKT network,
- Signaling by Receptor Tyrosine Kinases,
- Adaptive Immune System,
- PIP3 activates AKT signaling,
- Metabolism of RNA,
- Transcriptional regulation by RUNX2,
- Mitotic G1 phase and G1/S transition,
- Signaling by GPCR,
- Regulation of TP53 Activity through Association with Co-factors,
- Disease,
- Translocation of SLC2A4 (GLUT4) to the plasma membrane,
- Metabolism of nitric oxide: NOS3 activation and regulation,
- Signaling by PTK6,
- Constitutive Signaling by AKT1 E17K in Cancer,
- Integrin signaling
Gene --> GO terms.
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
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Mouse Gene --> Allele [Phenotype]
Other
96 Pathways
- Interleukin-4 and Interleukin-13 signaling,
- Cytokine Signaling in Immune system,
- RUNX2 regulates genes involved in cell migration,
- G beta:gamma signalling through PI3Kgamma,
- KSRP (KHSRP) binds and destabilizes mRNA,
- Costimulation by the CD28 family,
- Activation of BH3-only proteins,
- Signal Transduction,
- Metabolism of vitamins and cofactors,
- G-protein beta:gamma signalling,
- Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation,
- Signaling by ERBB2,
- Extra-nuclear estrogen signaling,
- Signaling by Interleukins,
- TP53 Regulates Metabolic Genes,
- Negative regulation of NOTCH4 signaling,
- Cyclin E associated events during G1/S transition ,
- VEGFA-VEGFR2 Pathway,
- Apoptosis,
- Cell Cycle,
- AKT-mediated inactivation of FOXO1A,
- CD28 co-stimulation,
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling,
- Intrinsic Pathway for Apoptosis,
- GPCR downstream signalling,
- Regulation of mRNA stability by proteins that bind AU-rich elements,
- Diseases of signal transduction by growth factor receptors and second messengers,
- Regulation of PTEN stability and activity,
- FOXO-mediated transcription,
- Immune System,
- ESR-mediated signaling,
- VEGFR2 mediated vascular permeability,
- Cell Cycle, Mitotic,
- G1/S Transition,
- Estrogen-dependent nuclear events downstream of ESR-membrane signaling,
- Signaling by NOTCH4,
- Activation of BAD and translocation to mitochondria ,
- Cyclin A:Cdk2-associated events at S phase entry,
- Metabolism,
- Vesicle-mediated transport,
- Intracellular signaling by second messengers,
- MTOR signalling,
- Downregulation of ERBB2:ERBB3 signaling,
- Regulation of beta-cell development,
- Transcriptional Regulation by TP53,
- Regulation of TP53 Expression and Degradation,
- Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA,
- S Phase,
- Gene expression (Transcription),
- AKT phosphorylates targets in the nucleus,
- Rab regulation of trafficking,
- Signaling by VEGF,
- Regulation of gene expression in beta cells,
- Signaling by Nuclear Receptors,
- Generic Transcription Pathway,
- Programmed Cell Death,
- Hemostasis,
- CTLA4 inhibitory signaling,
- Signaling by NOTCH,
- CD28 dependent PI3K/Akt signaling,
- Developmental Biology,
- Regulation of TP53 Activity through Acetylation,
- Metabolism of cofactors,
- PTEN Regulation,
- RAB GEFs exchange GTP for GDP on RABs,
- PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1,
- PI3K/AKT Signaling in Cancer,
- RNA Polymerase II Transcription,
- Regulation of TP53 Degradation,
- eNOS activation,
- Membrane Trafficking,
- Signaling by WNT,
- Platelet activation, signaling and aggregation,
- Signaling by Non-Receptor Tyrosine Kinases,
- TCF dependent signaling in response to WNT,
- Downregulation of ERBB2 signaling,
- Deactivation of the beta-catenin transactivating complex,
- Regulation of TP53 Activity,
- Platelet Aggregation (Plug Formation),
- Regulation of localization of FOXO transcription factors,
- AKT phosphorylates targets in the cytosol,
- Negative regulation of the PI3K/AKT network,
- Signaling by Receptor Tyrosine Kinases,
- Adaptive Immune System,
- PIP3 activates AKT signaling,
- Metabolism of RNA,
- Transcriptional regulation by RUNX2,
- Mitotic G1 phase and G1/S transition,
- Signaling by GPCR,
- Regulation of TP53 Activity through Association with Co-factors,
- Disease,
- Translocation of SLC2A4 (GLUT4) to the plasma membrane,
- Metabolism of nitric oxide: NOS3 activation and regulation,
- Signaling by PTK6,
- Constitutive Signaling by AKT1 E17K in Cancer,
- Integrin signaling
