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Function
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132 Pathways
- Regulation of TP53 Activity through Association with Co-factors,
- PTEN Regulation,
- Progesterone-mediated oocyte maturation,
- Disease,
- Toll-like receptor signaling pathway,
- Constitutive Signaling by AKT1 E17K in Cancer,
- VEGFR2 mediated vascular permeability,
- Glioma,
- T cell receptor signaling pathway,
- Signal Transduction,
- G beta:gamma signalling through PI3Kgamma,
- Chagas disease American trypanosomiasis,
- Chemokine signaling pathway,
- MAPK signaling pathway,
- Programmed Cell Death,
- Small cell lung cancer,
- Estrogen-dependent nuclear events downstream of ESR-membrane signaling,
- Renal cell carcinoma,
- PIP3 activates AKT signaling,
- Deactivation of the beta-catenin transactivating complex,
- CD28 co-stimulation,
- Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation,
- Costimulation by the CD28 family,
- Negative regulation of NOTCH4 signaling,
- Mitotic G1 phase and G1/S transition,
- CTLA4 inhibitory signaling,
- Hepatitis C,
- Integrin signaling,
- Regulation of mRNA stability by proteins that bind AU-rich elements,
- Cytokine Signaling in Immune system,
- Downregulation of ERBB2 signaling,
- Rab regulation of trafficking,
- Non-small cell lung cancer,
- Regulation of gene expression in beta cells,
- Toxoplasmosis,
- Diseases of signal transduction by growth factor receptors and second messengers,
- Intrinsic Pathway for Apoptosis,
- Negative regulation of the PI3K/AKT network,
- Signaling by Non-Receptor Tyrosine Kinases,
- mTOR signaling pathway,
- Neurotrophin signaling pathway,
- Cyclin A:Cdk2-associated events at S phase entry,
- Regulation of PTEN stability and activity,
- Generic Transcription Pathway,
- Signaling by PTK6,
- Developmental Biology,
- Apoptosis,
- Translocation of SLC2A4 (GLUT4) to the plasma membrane,
- Signaling by NOTCH,
- Adaptive Immune System,
- S Phase,
- Melanoma,
- Transcriptional Regulation by TP53,
- Extra-nuclear estrogen signaling,
- Colorectal cancer,
- Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA,
- CD28 dependent PI3K/Akt signaling,
- Vesicle-mediated transport,
- Metabolism of RNA,
- Endometrial cancer,
- Platelet activation, signaling and aggregation,
- Signaling by VEGF,
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling,
- Signaling by GPCR,
- Activation of BAD and translocation to mitochondria ,
- Pancreatic cancer,
- Acute myeloid leukemia,
- Membrane Trafficking,
- Pathways in cancer,
- Gene expression (Transcription),
- AKT phosphorylates targets in the cytosol,
- Prostate cancer,
- Carbohydrate digestion and absorption,
- TCF dependent signaling in response to WNT,
- RUNX2 regulates genes involved in cell migration,
- Signaling by WNT,
- G-protein beta:gamma signalling,
- AKT phosphorylates targets in the nucleus,
- eNOS activation,
- VEGF signaling pathway,
- ErbB signaling pathway,
- Jak-STAT signaling pathway,
- Signaling by Nuclear Receptors,
- TP53 Regulates Metabolic Genes,
- FOXO-mediated transcription,
- ESR-mediated signaling,
- Interleukin-4 and Interleukin-13 signaling,
- Regulation of TP53 Activity,
- Downregulation of ERBB2:ERBB3 signaling,
- Signaling by Interleukins,
- Adipocytokine signaling pathway,
- G1/S Transition,
- Focal adhesion,
- Platelet Aggregation (Plug Formation),
- Regulation of TP53 Expression and Degradation,
- Regulation of TP53 Activity through Acetylation,
- VEGFA-VEGFR2 Pathway,
- RNA Polymerase II Transcription,
- Metabolism of nitric oxide: eNOS activation and regulation,
- Activation of BH3-only proteins,
- Signaling by ERBB2,
- Regulation of beta-cell development,
- Tight junction,
- Cyclin E associated events during G1/S transition ,
- Apoptosis,
- Cell Cycle,
- Fc gamma R-mediated phagocytosis,
- Signaling by Receptor Tyrosine Kinases,
- Fc epsilon RI signaling pathway,
- Metabolism of vitamins and cofactors,
- KSRP (KHSRP) binds and destabilizes mRNA,
- Transcriptional regulation by RUNX2,
- Signaling by NOTCH4,
- Immune System,
- AKT-mediated inactivation of FOXO1A,
- mTOR signalling,
- Measles,
- Metabolism of cofactors,
- RAB GEFs exchange GTP for GDP on RABs,
- Intracellular signaling by second messengers,
- Metabolism,
- GPCR downstream signalling,
- Osteoclast differentiation,
- Insulin signaling pathway,
- Cell Cycle, Mitotic,
- B cell receptor signaling pathway,
- PI3K/AKT Signaling in Cancer,
- Regulation of localization of FOXO transcription factors,
- Chronic myeloid leukemia,
- Hemostasis,
- Regulation of TP53 Degradation,
- PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1
Gene --> GO terms.
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
Genomics
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Gene --> Chromosomal location.
Gene --> GO terms.
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Disease
Gene (Hum OR Rat) --> Mouse Allele (Phenotype)
Gene --> Alleles and Disease (clinVar data)
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
Other
132 Pathways
- Regulation of TP53 Activity through Association with Co-factors,
- PTEN Regulation,
- Progesterone-mediated oocyte maturation,
- Disease,
- Toll-like receptor signaling pathway,
- Constitutive Signaling by AKT1 E17K in Cancer,
- VEGFR2 mediated vascular permeability,
- Glioma,
- T cell receptor signaling pathway,
- Signal Transduction,
- G beta:gamma signalling through PI3Kgamma,
- Chagas disease American trypanosomiasis,
- Chemokine signaling pathway,
- MAPK signaling pathway,
- Programmed Cell Death,
- Small cell lung cancer,
- Estrogen-dependent nuclear events downstream of ESR-membrane signaling,
- Renal cell carcinoma,
- PIP3 activates AKT signaling,
- Deactivation of the beta-catenin transactivating complex,
- CD28 co-stimulation,
- Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation,
- Costimulation by the CD28 family,
- Negative regulation of NOTCH4 signaling,
- Mitotic G1 phase and G1/S transition,
- CTLA4 inhibitory signaling,
- Hepatitis C,
- Integrin signaling,
- Regulation of mRNA stability by proteins that bind AU-rich elements,
- Cytokine Signaling in Immune system,
- Downregulation of ERBB2 signaling,
- Rab regulation of trafficking,
- Non-small cell lung cancer,
- Regulation of gene expression in beta cells,
- Toxoplasmosis,
- Diseases of signal transduction by growth factor receptors and second messengers,
- Intrinsic Pathway for Apoptosis,
- Negative regulation of the PI3K/AKT network,
- Signaling by Non-Receptor Tyrosine Kinases,
- mTOR signaling pathway,
- Neurotrophin signaling pathway,
- Cyclin A:Cdk2-associated events at S phase entry,
- Regulation of PTEN stability and activity,
- Generic Transcription Pathway,
- Signaling by PTK6,
- Developmental Biology,
- Apoptosis,
- Translocation of SLC2A4 (GLUT4) to the plasma membrane,
- Signaling by NOTCH,
- Adaptive Immune System,
- S Phase,
- Melanoma,
- Transcriptional Regulation by TP53,
- Extra-nuclear estrogen signaling,
- Colorectal cancer,
- Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA,
- CD28 dependent PI3K/Akt signaling,
- Vesicle-mediated transport,
- Metabolism of RNA,
- Endometrial cancer,
- Platelet activation, signaling and aggregation,
- Signaling by VEGF,
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling,
- Signaling by GPCR,
- Activation of BAD and translocation to mitochondria ,
- Pancreatic cancer,
- Acute myeloid leukemia,
- Membrane Trafficking,
- Pathways in cancer,
- Gene expression (Transcription),
- AKT phosphorylates targets in the cytosol,
- Prostate cancer,
- Carbohydrate digestion and absorption,
- TCF dependent signaling in response to WNT,
- RUNX2 regulates genes involved in cell migration,
- Signaling by WNT,
- G-protein beta:gamma signalling,
- AKT phosphorylates targets in the nucleus,
- eNOS activation,
- VEGF signaling pathway,
- ErbB signaling pathway,
- Jak-STAT signaling pathway,
- Signaling by Nuclear Receptors,
- TP53 Regulates Metabolic Genes,
- FOXO-mediated transcription,
- ESR-mediated signaling,
- Interleukin-4 and Interleukin-13 signaling,
- Regulation of TP53 Activity,
- Downregulation of ERBB2:ERBB3 signaling,
- Signaling by Interleukins,
- Adipocytokine signaling pathway,
- G1/S Transition,
- Focal adhesion,
- Platelet Aggregation (Plug Formation),
- Regulation of TP53 Expression and Degradation,
- Regulation of TP53 Activity through Acetylation,
- VEGFA-VEGFR2 Pathway,
- RNA Polymerase II Transcription,
- Metabolism of nitric oxide: eNOS activation and regulation,
- Activation of BH3-only proteins,
- Signaling by ERBB2,
- Regulation of beta-cell development,
- Tight junction,
- Cyclin E associated events during G1/S transition ,
- Apoptosis,
- Cell Cycle,
- Fc gamma R-mediated phagocytosis,
- Signaling by Receptor Tyrosine Kinases,
- Fc epsilon RI signaling pathway,
- Metabolism of vitamins and cofactors,
- KSRP (KHSRP) binds and destabilizes mRNA,
- Transcriptional regulation by RUNX2,
- Signaling by NOTCH4,
- Immune System,
- AKT-mediated inactivation of FOXO1A,
- mTOR signalling,
- Measles,
- Metabolism of cofactors,
- RAB GEFs exchange GTP for GDP on RABs,
- Intracellular signaling by second messengers,
- Metabolism,
- GPCR downstream signalling,
- Osteoclast differentiation,
- Insulin signaling pathway,
- Cell Cycle, Mitotic,
- B cell receptor signaling pathway,
- PI3K/AKT Signaling in Cancer,
- Regulation of localization of FOXO transcription factors,
- Chronic myeloid leukemia,
- Hemostasis,
- Regulation of TP53 Degradation,
- PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1
