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Function
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85 Pathways
- Apoptosis,
- MTOR signalling,
- TP53 Regulates Metabolic Genes,
- Extra-nuclear estrogen signaling,
- Transcriptional Regulation by TP53,
- Regulation of PTEN stability and activity,
- Immune System,
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R),
- RUNX2 regulates genes involved in cell migration,
- Transcriptional regulation by RUNX2,
- CD28 dependent PI3K/Akt signaling,
- CD28 co-stimulation,
- Mitotic G1 phase and G1/S transition,
- PI3K/AKT Signaling in Cancer,
- Programmed Cell Death,
- PDE3B signalling,
- AKT phosphorylates targets in the cytosol,
- Inhibition of TSC complex formation by PKB,
- VEGFR2 mediated vascular permeability,
- Intrinsic Pathway for Apoptosis,
- Signaling by Insulin receptor,
- PTEN Regulation,
- Adaptive Immune System,
- Constitutive Signaling by AKT1 E17K in Cancer,
- IRS-mediated signalling,
- TCF dependent signaling in response to WNT,
- G beta:gamma signalling through PI3Kgamma,
- Activation of AKT2,
- PI3K Cascade,
- Negative regulation of the PI3K/AKT network,
- Cell Cycle,
- RNA Polymerase II Transcription,
- PIP3 activates AKT signaling,
- IGF1R signaling cascade,
- Estrogen-dependent nuclear events downstream of ESR-membrane signaling,
- Downregulation of ERBB2:ERBB3 signaling,
- Costimulation by the CD28 family,
- S Phase,
- Cytokine Signaling in Immune system,
- PKB-mediated events,
- Signaling by ERBB2,
- Regulation of gene expression in beta cells,
- Signal Transduction,
- VEGFA-VEGFR2 Pathway,
- Cyclin A:Cdk2-associated events at S phase entry,
- Intracellular signaling by second messengers,
- AKT-mediated inactivation of FOXO1A,
- Signaling by Nuclear Receptors,
- ESR-mediated signaling,
- Diseases of signal transduction by growth factor receptors and second messengers,
- Signaling by WNT,
- Regulation of TP53 Activity,
- Regulation of beta-cell development,
- Vesicle-mediated transport,
- Signaling by GPCR,
- Developmental Biology,
- AKT phosphorylates targets in the nucleus,
- Activation of BH3-only proteins,
- Generic Transcription Pathway,
- Signaling by Receptor Tyrosine Kinases,
- Regulation of TP53 Expression and Degradation,
- G-protein beta:gamma signalling,
- Regulation of TP53 Activity through Association with Co-factors,
- Signaling by VEGF,
- Disease,
- Regulation of TP53 Activity through Acetylation,
- Translocation of SLC2A4 (GLUT4) to the plasma membrane,
- IRS-related events triggered by IGF1R,
- Regulation of TP53 Degradation,
- Gene expression (Transcription),
- Cell Cycle, Mitotic,
- Cyclin E associated events during G1/S transition ,
- RAB GEFs exchange GTP for GDP on RABs,
- Rab regulation of trafficking,
- Insulin receptor signalling cascade,
- FLT3 Signaling,
- Activation of BAD and translocation to mitochondria ,
- Deactivation of the beta-catenin transactivating complex,
- CTLA4 inhibitory signaling,
- Membrane Trafficking,
- Regulation of localization of FOXO transcription factors,
- Downregulation of ERBB2 signaling,
- G1/S Transition,
- GPCR downstream signalling,
- FOXO-mediated transcription
Gene --> GO terms.
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
Genomics
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Gene --> Chromosomal location.
Gene --> GO terms.
Gene --> Overlapping genes.
Disease
Gene (Hum OR Rat) --> Mouse Allele (Phenotype)
Gene --> Alleles and Disease (clinVar data)
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
Other
85 Pathways
- Apoptosis,
- MTOR signalling,
- TP53 Regulates Metabolic Genes,
- Extra-nuclear estrogen signaling,
- Transcriptional Regulation by TP53,
- Regulation of PTEN stability and activity,
- Immune System,
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R),
- RUNX2 regulates genes involved in cell migration,
- Transcriptional regulation by RUNX2,
- CD28 dependent PI3K/Akt signaling,
- CD28 co-stimulation,
- Mitotic G1 phase and G1/S transition,
- PI3K/AKT Signaling in Cancer,
- Programmed Cell Death,
- PDE3B signalling,
- AKT phosphorylates targets in the cytosol,
- Inhibition of TSC complex formation by PKB,
- VEGFR2 mediated vascular permeability,
- Intrinsic Pathway for Apoptosis,
- Signaling by Insulin receptor,
- PTEN Regulation,
- Adaptive Immune System,
- Constitutive Signaling by AKT1 E17K in Cancer,
- IRS-mediated signalling,
- TCF dependent signaling in response to WNT,
- G beta:gamma signalling through PI3Kgamma,
- Activation of AKT2,
- PI3K Cascade,
- Negative regulation of the PI3K/AKT network,
- Cell Cycle,
- RNA Polymerase II Transcription,
- PIP3 activates AKT signaling,
- IGF1R signaling cascade,
- Estrogen-dependent nuclear events downstream of ESR-membrane signaling,
- Downregulation of ERBB2:ERBB3 signaling,
- Costimulation by the CD28 family,
- S Phase,
- Cytokine Signaling in Immune system,
- PKB-mediated events,
- Signaling by ERBB2,
- Regulation of gene expression in beta cells,
- Signal Transduction,
- VEGFA-VEGFR2 Pathway,
- Cyclin A:Cdk2-associated events at S phase entry,
- Intracellular signaling by second messengers,
- AKT-mediated inactivation of FOXO1A,
- Signaling by Nuclear Receptors,
- ESR-mediated signaling,
- Diseases of signal transduction by growth factor receptors and second messengers,
- Signaling by WNT,
- Regulation of TP53 Activity,
- Regulation of beta-cell development,
- Vesicle-mediated transport,
- Signaling by GPCR,
- Developmental Biology,
- AKT phosphorylates targets in the nucleus,
- Activation of BH3-only proteins,
- Generic Transcription Pathway,
- Signaling by Receptor Tyrosine Kinases,
- Regulation of TP53 Expression and Degradation,
- G-protein beta:gamma signalling,
- Regulation of TP53 Activity through Association with Co-factors,
- Signaling by VEGF,
- Disease,
- Regulation of TP53 Activity through Acetylation,
- Translocation of SLC2A4 (GLUT4) to the plasma membrane,
- IRS-related events triggered by IGF1R,
- Regulation of TP53 Degradation,
- Gene expression (Transcription),
- Cell Cycle, Mitotic,
- Cyclin E associated events during G1/S transition ,
- RAB GEFs exchange GTP for GDP on RABs,
- Rab regulation of trafficking,
- Insulin receptor signalling cascade,
- FLT3 Signaling,
- Activation of BAD and translocation to mitochondria ,
- Deactivation of the beta-catenin transactivating complex,
- CTLA4 inhibitory signaling,
- Membrane Trafficking,
- Regulation of localization of FOXO transcription factors,
- Downregulation of ERBB2 signaling,
- G1/S Transition,
- GPCR downstream signalling,
- FOXO-mediated transcription
