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Function
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121 Pathways
- Colorectal cancer,
- Membrane Trafficking,
- mTOR signalling,
- VEGFR2 mediated vascular permeability,
- Rab regulation of trafficking,
- Adipocytokine signaling pathway,
- Immune System,
- Renal cell carcinoma,
- FOXO-mediated transcription,
- PDE3B signalling,
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R),
- ErbB signaling pathway,
- Deactivation of the beta-catenin transactivating complex,
- G1/S Transition,
- Extra-nuclear estrogen signaling,
- Downregulation of ERBB2 signaling,
- Signaling by WNT,
- Regulation of beta-cell development,
- Regulation of TP53 Expression and Degradation,
- Signal Transduction,
- Apoptosis,
- Toll-like receptor signaling pathway,
- mTOR signaling pathway,
- Chronic myeloid leukemia,
- Regulation of TP53 Degradation,
- Chemokine signaling pathway,
- FLT3 Signaling,
- Regulation of TP53 Activity through Acetylation,
- Pathways in cancer,
- Insulin signaling pathway,
- B cell receptor signaling pathway,
- Jak-STAT signaling pathway,
- Activation of AKT2,
- Transcriptional regulation by RUNX2,
- Progesterone-mediated oocyte maturation,
- Vesicle-mediated transport,
- Intracellular signaling by second messengers,
- Apoptosis,
- PIP3 activates AKT signaling,
- Activation of BH3-only proteins,
- Focal adhesion,
- Hepatitis C,
- IRS-related events triggered by IGF1R,
- Negative regulation of the PI3K/AKT network,
- PTEN Regulation,
- TCF dependent signaling in response to WNT,
- RAB GEFs exchange GTP for GDP on RABs,
- Carbohydrate digestion and absorption,
- T cell receptor signaling pathway,
- Osteoclast differentiation,
- Programmed Cell Death,
- Disease,
- AKT phosphorylates targets in the cytosol,
- Signaling by GPCR,
- RUNX2 regulates genes involved in cell migration,
- Intrinsic Pathway for Apoptosis,
- ESR-mediated signaling,
- Activation of BAD and translocation to mitochondria ,
- Small cell lung cancer,
- Regulation of gene expression in beta cells,
- Generic Transcription Pathway,
- Chagas disease American trypanosomiasis,
- Glioma,
- Downregulation of ERBB2:ERBB3 signaling,
- VEGF signaling pathway,
- Acute myeloid leukemia,
- PI3K/AKT Signaling in Cancer,
- Fc gamma R-mediated phagocytosis,
- Costimulation by the CD28 family,
- Signaling by Receptor Tyrosine Kinases,
- Cytokine Signaling in Immune system,
- Cell Cycle, Mitotic,
- IRS-mediated signalling,
- Cyclin E associated events during G1/S transition ,
- Adaptive Immune System,
- Signaling by ERBB2,
- Gene expression (Transcription),
- CD28 dependent PI3K/Akt signaling,
- Melanoma,
- Cyclin A:Cdk2-associated events at S phase entry,
- Regulation of PTEN stability and activity,
- RNA Polymerase II Transcription,
- G beta:gamma signalling through PI3Kgamma,
- AKT phosphorylates targets in the nucleus,
- GPCR downstream signalling,
- TP53 Regulates Metabolic Genes,
- Toxoplasmosis,
- CTLA4 inhibitory signaling,
- Regulation of localization of FOXO transcription factors,
- Transcriptional Regulation by TP53,
- Estrogen-dependent nuclear events downstream of ESR-membrane signaling,
- AKT-mediated inactivation of FOXO1A,
- Non-small cell lung cancer,
- Regulation of TP53 Activity,
- Cell Cycle,
- PI3K Cascade,
- CD28 co-stimulation,
- Diseases of signal transduction by growth factor receptors and second messengers,
- Signaling by VEGF,
- Mitotic G1 phase and G1/S transition,
- MAPK signaling pathway,
- Developmental Biology,
- S Phase,
- IGF1R signaling cascade,
- Prostate cancer,
- Insulin receptor signalling cascade,
- Pancreatic cancer,
- Neurotrophin signaling pathway,
- Constitutive Signaling by AKT1 E17K in Cancer,
- Translocation of SLC2A4 (GLUT4) to the plasma membrane,
- Measles,
- Inhibition of TSC complex formation by PKB,
- VEGFA-VEGFR2 Pathway,
- G-protein beta:gamma signalling,
- Signaling by Insulin receptor,
- Regulation of TP53 Activity through Association with Co-factors,
- Endometrial cancer,
- Tight junction,
- Fc epsilon RI signaling pathway,
- PKB-mediated events,
- Signaling by Nuclear Receptors
Gene --> GO terms.
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
Genomics
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Disease
Gene (Hum OR Rat) --> Mouse Allele (Phenotype)
Gene --> Alleles and Disease (clinVar data)
Gene -> HPO annotation (Human Phenotype Ontology)
Mouse Gene --> Allele [Phenotype]
Other
121 Pathways
- Colorectal cancer,
- Membrane Trafficking,
- mTOR signalling,
- VEGFR2 mediated vascular permeability,
- Rab regulation of trafficking,
- Adipocytokine signaling pathway,
- Immune System,
- Renal cell carcinoma,
- FOXO-mediated transcription,
- PDE3B signalling,
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R),
- ErbB signaling pathway,
- Deactivation of the beta-catenin transactivating complex,
- G1/S Transition,
- Extra-nuclear estrogen signaling,
- Downregulation of ERBB2 signaling,
- Signaling by WNT,
- Regulation of beta-cell development,
- Regulation of TP53 Expression and Degradation,
- Signal Transduction,
- Apoptosis,
- Toll-like receptor signaling pathway,
- mTOR signaling pathway,
- Chronic myeloid leukemia,
- Regulation of TP53 Degradation,
- Chemokine signaling pathway,
- FLT3 Signaling,
- Regulation of TP53 Activity through Acetylation,
- Pathways in cancer,
- Insulin signaling pathway,
- B cell receptor signaling pathway,
- Jak-STAT signaling pathway,
- Activation of AKT2,
- Transcriptional regulation by RUNX2,
- Progesterone-mediated oocyte maturation,
- Vesicle-mediated transport,
- Intracellular signaling by second messengers,
- Apoptosis,
- PIP3 activates AKT signaling,
- Activation of BH3-only proteins,
- Focal adhesion,
- Hepatitis C,
- IRS-related events triggered by IGF1R,
- Negative regulation of the PI3K/AKT network,
- PTEN Regulation,
- TCF dependent signaling in response to WNT,
- RAB GEFs exchange GTP for GDP on RABs,
- Carbohydrate digestion and absorption,
- T cell receptor signaling pathway,
- Osteoclast differentiation,
- Programmed Cell Death,
- Disease,
- AKT phosphorylates targets in the cytosol,
- Signaling by GPCR,
- RUNX2 regulates genes involved in cell migration,
- Intrinsic Pathway for Apoptosis,
- ESR-mediated signaling,
- Activation of BAD and translocation to mitochondria ,
- Small cell lung cancer,
- Regulation of gene expression in beta cells,
- Generic Transcription Pathway,
- Chagas disease American trypanosomiasis,
- Glioma,
- Downregulation of ERBB2:ERBB3 signaling,
- VEGF signaling pathway,
- Acute myeloid leukemia,
- PI3K/AKT Signaling in Cancer,
- Fc gamma R-mediated phagocytosis,
- Costimulation by the CD28 family,
- Signaling by Receptor Tyrosine Kinases,
- Cytokine Signaling in Immune system,
- Cell Cycle, Mitotic,
- IRS-mediated signalling,
- Cyclin E associated events during G1/S transition ,
- Adaptive Immune System,
- Signaling by ERBB2,
- Gene expression (Transcription),
- CD28 dependent PI3K/Akt signaling,
- Melanoma,
- Cyclin A:Cdk2-associated events at S phase entry,
- Regulation of PTEN stability and activity,
- RNA Polymerase II Transcription,
- G beta:gamma signalling through PI3Kgamma,
- AKT phosphorylates targets in the nucleus,
- GPCR downstream signalling,
- TP53 Regulates Metabolic Genes,
- Toxoplasmosis,
- CTLA4 inhibitory signaling,
- Regulation of localization of FOXO transcription factors,
- Transcriptional Regulation by TP53,
- Estrogen-dependent nuclear events downstream of ESR-membrane signaling,
- AKT-mediated inactivation of FOXO1A,
- Non-small cell lung cancer,
- Regulation of TP53 Activity,
- Cell Cycle,
- PI3K Cascade,
- CD28 co-stimulation,
- Diseases of signal transduction by growth factor receptors and second messengers,
- Signaling by VEGF,
- Mitotic G1 phase and G1/S transition,
- MAPK signaling pathway,
- Developmental Biology,
- S Phase,
- IGF1R signaling cascade,
- Prostate cancer,
- Insulin receptor signalling cascade,
- Pancreatic cancer,
- Neurotrophin signaling pathway,
- Constitutive Signaling by AKT1 E17K in Cancer,
- Translocation of SLC2A4 (GLUT4) to the plasma membrane,
- Measles,
- Inhibition of TSC complex formation by PKB,
- VEGFA-VEGFR2 Pathway,
- G-protein beta:gamma signalling,
- Signaling by Insulin receptor,
- Regulation of TP53 Activity through Association with Co-factors,
- Endometrial cancer,
- Tight junction,
- Fc epsilon RI signaling pathway,
- PKB-mediated events,
- Signaling by Nuclear Receptors
