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Gene : EYA3 Homo sapiens

Name  ? EYA transcriptional coactivator and phosphatase 3 Cytological Location  1p35.3
Brief Description  EYA transcriptional coactivator and phosphatase 3
Description  This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013]
  • synonyms:
  • DKFZp686C132,
  • EYA3,
  • U81602,
  • eyes absent homolog 3 (Drosophila),
  • uc001bpi.3,
  • NM_001990,
  • eyes absent (Drosophila) homolog 3,
  • HGNC:3521,
  • OTTHUMG00000003916
  • identifiers:
  • 2140,
  • ENSG00000158161,
  • EYA3

Genome feature

Region: gene ? Length: 118328  
Location: 1:27970344-28088671 reverse strand Cyto location: 1p35.3

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results