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Gene : ACSL4 Homo sapiens

Name  ? acyl-CoA synthetase long chain family member 4 Cytological Location  Xq23
Brief Description  acyl-CoA synthetase long chain family member 4
Description  The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the cognitive disability or Alport syndrome. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jan 2016]
  • synonyms:
  • MRX63,
  • OTTHUMG00000022190,
  • HGNC:3571,
  • fatty-acid-Coenzyme A ligase, long-chain 4,
  • FACL4,
  • ACS4,
  • mental retardation, X-linked 68,
  • FACL4,
  • lignoceroyl-CoA synthase,
  • ACS4,
  • MRX68,
  • LACS4,
  • long-chain fatty-acid-Coenzyme A ligase 4,
  • LACS4,
  • BC034959,
  • NM_004458,
  • ACSL4,
  • MRX68,
  • mental retardation, X-linked 63,
  • MRX63,
  • uc004eoi.3
  • identifiers:
  • 2182,
  • ENSG00000068366,
  • ACSL4

Genome feature

Region: gene ? Length: 91991  
Location: X:109641335-109733325 reverse strand Cyto location: Xq23

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1 Diseases

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430 SNPs

5 Cross References

18 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results