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Gene : FAP Homo sapiens

Name  ? fibroblast activation protein alpha Cytological Location  2q24.2
Brief Description  fibroblast activation protein alpha
Description  The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
  • synonyms:
  • FAP,
  • DPPIV,
  • OTTHUMG00000153890,
  • SIMP,
  • uc002ucd.3,
  • seprase,
  • fibroblast activation protein, alpha,
  • DPPIV,
  • FAPA,
  • NM_001291807,
  • U09278,
  • FAPalpha,
  • HGNC:3590
  • identifiers:
  • 2191,
  • ENSG00000078098,
  • FAP

Genome feature

Region: gene ? Length: 72789  
Location: 2:162170684-162243472 reverse strand Cyto location: 2q24.2


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Function

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

0 Pathways

3753 SN Ps

5 Cross References

17 Data Sets

12 Homologues

0 Located Features

97 Rna Seq Results