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Gene : BRAT1 Homo sapiens

Name  ? BRCA1 associated ATM activator 1 Cytological Location  7p22.3
Brief Description  BRCA1 associated ATM activator 1
Description  The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012]
  • synonyms:
  • BRCA1-associated ATM activator 1,
  • MGC22916,
  • BRAT1,
  • BAAT1,
  • BRCA1-associated protein required for ATM activation protein 1,
  • BAAT1,
  • OTTHUMG00000119091,
  • C7orf27,
  • HGNC:21701,
  • BC015632,
  • C7orf27,
  • uc003smi.4,
  • NM_152743,
  • RMFSL,
  • chromosome 7 open reading frame 27
  • identifiers:
  • 221927,
  • ENSG00000106009,
  • BRAT1

Genome feature

Region: gene ? Length: 17944  
Location: 7:2537810-2555753 reverse strand Cyto location: 7p22.3

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

688 SN Ps

5 Cross References

18 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results