help  | about  | cite  | software

Gene : FDFT1 Homo sapiens

Name  ? farnesyl-diphosphate farnesyltransferase 1 Cytological Location  8p23.1
Brief Description  farnesyl-diphosphate farnesyltransferase 1
Description  This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • squalene synthase,
  • NM_001287742,
  • OTTHUMG00000090801,
  • SQSD,
  • SQS,
  • uc033bcg.2,
  • ERG9,
  • FDFT1,
  • SQS,
  • X69141,
  • HGNC:3629,
  • SS,
  • DGPT
  • identifiers:
  • 2222,
  • ENSG00000079459,
  • FDFT1

Genome feature

Region: gene ? Length: 43737  
Location: 8:11795573-11839309 Cyto location: 8p23.1


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

3753 SN Ps

5 Cross References

18 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results