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Gene : FECH Homo sapiens

Name  ? ferrochelatase Cytological Location  18q21.31
Brief Description  ferrochelatase
Description  The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.[provided by RefSeq, May 2010]
  • synonyms:
  • FCE,
  • D00726,
  • HGNC:3647,
  • NM_000140,
  • EPP1,
  • FECH,
  • uc002lgq.5,
  • EPP,
  • OTTHUMG00000132740,
  • protoporphyria,
  • ferrochelatase (protoporphyria)
  • identifiers:
  • 2235,
  • ENSG00000066926,
  • FECH

Genome feature

Region: gene ? Length: 42332  
Location: 18:57544377-57586708 reverse strand Cyto location: 18q21.31


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

538 SN Ps

5 Cross References

20 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results