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Gene : FES Homo sapiens

Name  ? FES proto-oncogene, tyrosine kinase Cytological Location  15q26.1
Brief Description  FES proto-oncogene, tyrosine kinase
Description  This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009]
  • synonyms:
  • HGNC:3657,
  • FPS,
  • uc002bpv.4,
  • feline sarcoma oncogene,
  • OTTHUMG00000044456,
  • feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog,
  • NM_002005,
  • FES,
  • c-fes/fps protein,
  • X52192,
  • FPS,
  • Oncogene FES, feline sarcoma virus
  • identifiers:
  • 2242,
  • ENSG00000182511,
  • FES

Genome feature

Region: gene ? Length: 11356  
Location: 15:90884421-90895776 Cyto location: 15q26.1


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Disease

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3753 SN Ps

5 Cross References

18 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results