help  | about  | cite  | software

Gene : FGF3 Homo sapiens

Name  ? fibroblast growth factor 3 Cytological Location  11q13.3
Brief Description  fibroblast growth factor 3
Description  The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation. [provided by RefSeq, Jul 2008]
  • synonyms:
  • uc001oph.4,
  • HGNC:3681,
  • NM_005247,
  • fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog),
  • oncogene INT2,
  • V-INT2 murine mammary tumor virus integration site oncogene homolog,
  • INT2,
  • OTTHUMG00000167888,
  • INT2,
  • murine mammary tumor virus integration site 2, mouse,
  • HBGF-3,
  • FGF3,
  • INT-2 proto-oncogene protein,
  • HBGF-3
  • identifiers:
  • 2248,
  • ENSG00000186895,
  • FGF3

Genome feature

Region: gene ? Length: 9449  
Location: 11:69809968-69819416 reverse strand Cyto location: 11q13.3


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

51 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

51 Pathways

193 SN Ps

5 Cross References

18 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results