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Gene : FGF3 Homo sapiens

Name  ? fibroblast growth factor 3 Cytological Location  11q13.3
Brief Description  fibroblast growth factor 3
Description  The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation. [provided by RefSeq, Jul 2008]
  • synonyms:
  • uc001oph.4,
  • HGNC:3681,
  • NM_005247,
  • fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog),
  • oncogene INT2,
  • V-INT2 murine mammary tumor virus integration site oncogene homolog,
  • INT2,
  • OTTHUMG00000167888,
  • INT2,
  • murine mammary tumor virus integration site 2, mouse,
  • HBGF-3,
  • FGF3,
  • INT-2 proto-oncogene protein,
  • HBGF-3
  • identifiers:
  • 2248,
  • ENSG00000186895,
  • FGF3

Genome feature

Region: gene ? Length: 9449  
Location: 11:69809968-69819416 reverse strand Cyto location: 11q13.3

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51 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

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Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



51 Pathways

193 SN Ps

5 Cross References

18 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results