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Gene : FGF4 Homo sapiens

Name  ? fibroblast growth factor 4 Cytological Location  11q13.3
Brief Description  fibroblast growth factor 4
Description  The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq, Jul 2008]
  • synonyms:
  • HSTF-1,
  • M17446,
  • HST-1,
  • KFGF,
  • HBGF-4,
  • HSTF1,
  • HST-1,
  • heparin secretory transforming protein 1,
  • HSTF1,
  • transforming protein KS3,
  • HST,
  • K-FGF,
  • uc001opg.2,
  • HST,
  • K-FGF,
  • NM_002007,
  • human stomach cancer, transforming factor from FGF-related oncogene,
  • OTTHUMG00000167887,
  • kaposi sarcoma oncogene,
  • KFGF,
  • FGF-4,
  • FGF4,
  • HBGF-4,
  • HGNC:3682
  • identifiers:
  • 2249,
  • ENSG00000075388,
  • FGF4

Genome feature

Region: gene ? Length: 4320  
Location: 11:69771022-69775341 reverse strand Cyto location: 11q13.3

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75 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

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Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



75 Pathways

57 SN Ps

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results