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Gene : FGFR4 Homo sapiens

Name  ? fibroblast growth factor receptor 4 Cytological Location  5q35.2
Brief Description  fibroblast growth factor receptor 4
Description  The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways, including cell proliferation, cell differentiation, cell migration, lipid metabolism, bile acid biosynthesis, vitamin D metabolism, glucose uptake, and phosphate homeostasis. This protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. [provided by RefSeq, Aug 2017]
  • synonyms:
  • JTK2,
  • HGNC:3691,
  • JTK2,
  • AF202063,
  • OTTHUMG00000151523,
  • TKF,
  • FGFR4,
  • CD334,
  • NM_001291980,
  • uc003mfm.4,
  • CD334
  • identifiers:
  • 2264,
  • ENSG00000160867,
  • FGFR4

Genome feature

Region: gene ? Length: 11230  
Location: 5:177086915-177098144 Cyto location: 5q35.2

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

18 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results