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Gene : FGG Homo sapiens

Name  ? fibrinogen gamma chain Cytological Location  4q32.1
Brief Description  fibrinogen gamma chain
Description  The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
  • synonyms:
  • OTTHUMG00000150329,
  • fibrinogen, gamma polypeptide,
  • uc003iog.4,
  • HGNC:3694,
  • NM_021870,
  • FGG
  • identifiers:
  • 2266,
  • ENSG00000171557,
  • FGG

Genome feature

Region: gene ? Length: 8675  
Location: 4:154604134-154612808 reverse strand Cyto location: 4q32.1


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Proteins

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SNPs

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Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Expression

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Other

290 SN Ps

5 Cross References

20 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results