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Gene : IKZF3 Homo sapiens

Name  ? IKAROS family zinc finger 3 Cytological Location  17q12-q21.1
Brief Description  IKAROS family zinc finger 3
Description  This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]
  • synonyms:
  • ZNFN1A3,
  • Aiolos,
  • AIO,
  • ZNFN1A3,
  • IKAROS family zinc finger 3 (Aiolos),
  • zinc finger protein, subfamily 1A, 3 (Aiolos),
  • OTTHUMG00000133250,
  • AF129512,
  • HGNC:13178,
  • IKZF3,
  • NM_012481,
  • uc002hsu.4
  • identifiers:
  • 22806,
  • ENSG00000161405,
  • IKZF3

Genome feature

Region: gene ? Length: 106598  
Location: 17:39757715-39864312 reverse strand Cyto location: 17q12-q21.1

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Ontology

Gene --> GO terms.



0 Pathways

281 SN Ps

5 Cross References

17 Data Sets

10 Homologues

0 Located Features

97 Rna Seq Results