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Gene : FKBP5 Homo sapiens

Name  ? FKBP prolyl isomerase 5 Cytological Location  6p21.31
Brief Description  FKBP prolyl isomerase 5
Description  The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]
  • synonyms:
  • AIG6,
  • FKBP51,
  • FKBP54,
  • FK506-binding protein 5,
  • PPIase,
  • FK506 binding protein 5,
  • P54,
  • Ptg-10,
  • NM_001145775,
  • Ptg-10,
  • P54,
  • uc003oky.3,
  • PPIase,
  • FKBP5,
  • FKBP51,
  • HGNC:3721,
  • U42031,
  • FKBP54,
  • OTTHUMG00000014576
  • identifiers:
  • 2289,
  • ENSG00000096060,
  • FKBP5

Genome feature

Region: gene ? Length: 154999  
Location: 6:35573585-35728583 reverse strand Cyto location: 6p21.31


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Disease

1 Diseases

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52 SN Ps

5 Cross References

18 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results