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Gene : CYFIP1 Homo sapiens

Name  ? cytoplasmic FMR1 interacting protein 1 Cytological Location  15q11.2
Brief Description  cytoplasmic FMR1 interacting protein 1
Description  This gene encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization.This protein also interacts with the Fragile X mental retardation protein (FMRP) and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including this gene is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of this gene has been observed in various human cancers and the encoded protein may inhibit tumor invasion. [provided by RefSeq, May 2017]
  • synonyms:
  • SRA1,
  • OTTHUMG00000129100,
  • SHYC,
  • CYFIP1,
  • HGNC:13759,
  • NM_014608,
  • KIAA0068,
  • P140SRA-1,
  • selective hybridizing clone,
  • uc001yus.5,
  • SRA-1,
  • P140SRA-1,
  • SHYC,
  • D38549,
  • cytoplasmic FMRP interacting protein 1
  • identifiers:
  • 23191,
  • ENSG00000273749,
  • CYFIP1

Genome feature

Region: gene ? Length: 113847  
Location: 15:22867052-22980898 reverse strand Cyto location: 15q11.2


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Proteins

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SNPs

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Disease

0 Diseases

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

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Other

763 SN Ps

5 Cross References

17 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results