help  | about  | cite  | software

Gene : GANAB Homo sapiens

Name  ? glucosidase II alpha subunit Cytological Location  11q12.3
Brief Description  glucosidase II alpha subunit
Description  This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease. [provided by RefSeq, Jul 2016]
  • synonyms:
  • KIAA0088,
  • HGNC:4138,
  • GluII,
  • GLUII,
  • uc001nub.5,
  • PKD3,
  • NM_198334,
  • AF144074,
  • G2AN,
  • GIIA,
  • G2AN,
  • glucosidase, alpha; neutral AB,
  • GIIA,
  • neutral alpha-glucosidase AB,
  • GANAB,
  • OTTHUMG00000167696
  • identifiers:
  • 23193,
  • ENSG00000089597,
  • GANAB

Genome feature

Region: gene ? Length: 21901  
Location: 11:62624826-62646726 reverse strand Cyto location: 11q12.3


Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

630 SN Ps

5 Cross References

20 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results