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Gene : FBXL7 Homo sapiens

Name  ? F-box and leucine rich repeat protein 7 Cytological Location  5p15.1
Brief Description  F-box and leucine rich repeat protein 7
Description  This gene encodes a member of the F-box protein family which is characterized by a 42-48 amino acid motif, the F-box, which binds to the S-phase kinase-associated protein 1 (Skp1) protein. The F-box proteins constitute one of the four subunits of E3 ubiquitin protein ligases called SCFs (SKP1-Cul1-F-box), which play a role in phosphorylation-dependent ubiquitination of proteins. The F-box proteins are divided into 3 subfamilies based on the other domain in the protein: F-box proteins that also have a WD-40 domain (Fbws subfamily), F-box proteins that also have leucine-rich repeats (Fbls subfamily) and F-box proteins that contain other motifs or lack known protein-interaction domains (Fbxs subfamily). The protein encoded by this gene belongs to the Fbls subfamily. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
  • synonyms:
  • FBL6,
  • KIAA0840,
  • uc003jfn.3,
  • FBL7,
  • NM_012304,
  • FBXL7,
  • FBL6,
  • AB020647,
  • OTTHUMG00000161798,
  • HGNC:13604,
  • FBL7
  • identifiers:
  • 23194,
  • ENSG00000183580,
  • FBXL7

Genome feature

Region: gene ? Length: 439617  
Location: 5:15500180-15939796 Cyto location: 5p15.1

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Gene -> HPO annotation (Human Phenotype Ontology)

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

16 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results