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Gene : CBX5 Homo sapiens

Name  ? chromobox 5 Cytological Location  12q13.13
Brief Description  chromobox 5
Description  This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • synonyms:
  • chromobox homolog 5,
  • HP1 alpha homolog (Drosophila),
  • HGNC:1555,
  • chromobox homolog 5 (HP1 alpha homolog, Drosophila),
  • OTTHUMG00000169700,
  • chromobox homolog 5 (Drosophila HP1 alpha),
  • NM_012117,
  • uc001sfk.6,
  • CBX5,
  • HP1-ALPHA,
  • HP1,
  • HEL25,
  • U26311,
  • HP1A,
  • HP1Hs-alpha,
  • HP1
  • identifiers:
  • 23468,
  • ENSG00000094916,
  • CBX5

Genome feature

Region: gene ? Length: 49181  
Location: 12:54230942-54280122 reverse strand Cyto location: 12q13.13

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0 Diseases

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Gene -> HPO annotation (Human Phenotype Ontology)

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64 SNPs

5 Cross References

15 Data Sets

7 Homologues

0 Located Features

97 Rna Seq Results