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Gene : CAPN7 Homo sapiens

Name  ? calpain 7 Cytological Location  3p25.1
Brief Description  calpain 7
Description  Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity. [provided by RefSeq, Jul 2008]
  • synonyms:
  • PalBH,
  • CALPAIN7,
  • CAPN7,
  • uc003bzn.4,
  • NM_014296,
  • PALBH,
  • homolog of Aspergillus Nidulans PALB,
  • AB028639,
  • calpain like protease,
  • HGNC:1484,
  • OTTHUMG00000129863
  • identifiers:
  • 23473,
  • ENSG00000131375,
  • CAPN7

Genome feature

Region: gene ? Length: 46671  
Location: 3:15206246-15252916 Cyto location: 3p25.1


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Function

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Gene --> Orthologues

Interactions

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Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

248 SN Ps

5 Cross References

15 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results