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Gene : FOLR1 Homo sapiens

Name  ? folate receptor alpha Cytological Location  11q13.4
Brief Description  folate receptor alpha
Description  The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]
  • synonyms:
  • FOLR,
  • FRalpha,
  • FBP,
  • uc001osa.3,
  • FOLR1,
  • folate receptor 1,
  • FOLR,
  • NM_016725,
  • J05013,
  • folate receptor 1 (adult),
  • FRĪ±,
  • HGNC:3791,
  • OTTHUMG00000167876
  • identifiers:
  • 2348,
  • ENSG00000110195,
  • FOLR1

Genome feature

Region: gene ? Length: 6615  
Location: 11:72189709-72196323 Cyto location: 11q13.4

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1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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99 SN Ps

5 Cross References

18 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results