help  | about  | cite  | software

Gene : CES3 Homo sapiens

Name  ? carboxylesterase 3 Cytological Location  16q22.1
Brief Description  carboxylesterase 3
Description  This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This gene is expressed in several tissues, particularly in colon, trachea and in brain, and the protein participates in colon and neural drug metabolism. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported, but the biological validity and/or full-length nature of some variants have not been determined.[provided by RefSeq, Jun 2010]
  • synonyms:
  • ES31,
  • NM_024922,
  • AK025389,
  • esterase 31,
  • CES3,
  • HGNC:1865,
  • FLJ21736,
  • brain carboxylesterase BR3,
  • OTTHUMG00000137525,
  • uc002eqt.4,
  • carboxylesterase 3 (brain),
  • ES31
  • identifiers:
  • 23491,
  • ENSG00000172828,
  • CES3

Genome feature

Region: gene ? Length: 13884  
Location: 16:66961266-66975149 Cyto location: 16q22.1

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



450 SN Ps

5 Cross References

16 Data Sets

29 Homologues

0 Located Features

97 Rna Seq Results