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Gene : FOLR2 Homo sapiens

Name  ? folate receptor beta Cytological Location  11q13.4
Brief Description  folate receptor beta
Description  The protein encoded by this gene is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • synonyms:
  • FBP,
  • FRĪ²,
  • FR-P3,
  • uc001ose.5,
  • HGNC:3793,
  • NM_000803,
  • FOLR2,
  • AK222539,
  • BETA-HFR,
  • FOLR1,
  • folate receptor 2 (fetal),
  • FBP/PL-1,
  • FRbeta,
  • OTTHUMG00000150394,
  • FR-BETA
  • identifiers:
  • 2350,
  • ENSG00000165457,
  • FOLR2

Genome feature

Region: gene ? Length: 5157  
Location: 11:72216794-72221950 Cyto location: 11q13.4


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Disease

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41 SN Ps

4 Cross References

14 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results