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Gene : CABIN1 Homo sapiens

Name  ? calcineurin binding protein 1 Cytological Location  22q11.23
Brief Description  calcineurin binding protein 1
Description  Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms. [provided by RefSeq, Jan 2011]
  • synonyms:
  • OTTHUMG00000150797,
  • CABIN1,
  • PPP3IN,
  • KB-318B8.7,
  • NM_012295,
  • KIAA0330,
  • PPP3IN,
  • CAIN,
  • AF072441,
  • uc002zzi.1,
  • HGNC:24187
  • identifiers:
  • 23523,
  • ENSG00000099991,
  • CABIN1

Genome feature

Region: gene ? Length: 167437  
Location: 22:24011192-24178628 Cyto location: 22q11.23


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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Expression

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Other

3756 SN Ps

5 Cross References

16 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results