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Gene : ALOX12 Homo sapiens

Name  ? arachidonate 12-lipoxygenase, 12S type Cytological Location  17p13.1
Brief Description  arachidonate 12-lipoxygenase, 12S type
Description  This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on different polyunsaturated fatty acid substrates to generate bioactive lipid mediators including eicosanoids and lipoxins. The encoded enzyme and its reaction products have been shown to regulate platelet function. Elevated expression of this gene has been observed in pancreatic islets derived from human diabetes patients. Allelic variants in this gene may be associated with susceptibility to toxoplasmosis. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]
  • synonyms:
  • uc002gdx.4,
  • 12S-LOX,
  • LOG12,
  • OTTHUMG00000102088,
  • platelet 12-LOX,
  • arachidonate 12-lipoxygenase,
  • M35418,
  • NM_000697,
  • 12S-LOX,
  • ALOX12,
  • 12-LOX,
  • HGNC:429,
  • Arachidonate 12-lipoxygenase, 12S-type
  • identifiers:
  • 239,
  • ENSG00000108839,
  • ALOX12

Genome feature

Region: gene ? Length: 16964  
Location: 17:6993791-7010754 Cyto location: 17p13.1

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



797 SN Ps

5 Cross References

17 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results