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Gene : DEFB114 Homo sapiens

Name  ? defensin beta 114 Cytological Location  6p12.3
Brief Description  defensin beta 114
Description  Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. The protein encoded by this gene is a beta-defensin with antimicrobial activity against E. coli, S. aureus, and C. albicans. The encoded protein also binds and neutralizes lipopolysaccharide (LPS), a factor involved in inflammatory diseases and male reproductive issues. [provided by RefSeq, Nov 2014]
  • synonyms:
  • DEFB-14,
  • DEFB-14,
  • NM_001037499,
  • uc011dwp.3,
  • OTTHUMG00000160209,
  • DQ012018,
  • DEFB14,
  • HGNC:18095,
  • defensin, beta 114,
  • DEFB114
  • identifiers:
  • 245928,
  • ENSG00000177684,
  • DEFB114

Genome feature

Region: gene ? Length: 3916  
Location: 6:49960249-49964164 reverse strand Cyto location: 6p12.3

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

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Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 SN Ps

4 Cross References

9 Data Sets

0 Homologues

0 Located Features

97 Rna Seq Results