help  | about  | cite  | software

Gene : ALOX15 Homo sapiens
Name  ? arachidonate 15-lipoxygenase Cytological Location  17p13.2
Brief Description  arachidonate 15-lipoxygenase
Description  This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on various polyunsaturated fatty acid substrates to generate various bioactive lipid mediators such as eicosanoids, hepoxilins, lipoxins, and other molecules. The encoded enzyme and its reaction products have been shown to regulate inflammation and immunity. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]
  • synonyms:
  • M23892,
  • 15-LOX-1,
  • NM_001140,
  • LOG15,
  • HGNC:433,
  • 15-LOX-1,
  • ALOX15,
  • uc010vse.3,
  • 15-LOX,
  • OTTHUMG00000090746,
  • 12-LOX
  • identifiers:
  • 246,
  • ENSG00000161905,
  • ALOX15

Genome feature

Region: gene ? Length: 10760  
Location: 17:4630919-4641678 reverse strand Cyto location: 17p13.2


Paste the following link
Lists
This Gene is in one list:
PL_BHF_UCL_cardiovascGenes (4103)

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer

Function

Gene Ontology Displayer

21 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.

Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

Homologue Displayer

Interactions

Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions

Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.

 

Other

21 Pathways

3740 SNPs

5 Cross References

17 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results





Funding: InterMine has been developed principally through support of the Wellcome Trust. Complementary projects have been funded by the NIH/NHGRI and the BBSRC.

An ELIXIR-UK resource

© 2002 - 2019 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom