help  | about  | cite  | software

Gene : ALPP Homo sapiens

Name  ? alkaline phosphatase, placental Cytological Location  2q37.1
Brief Description  alkaline phosphatase, placental
Description  The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Jan 2015]
  • synonyms:
  • Regan isozyme,
  • OTTHUMG00000133255,
  • placental alkaline phosphatase,
  • ALPI,
  • M14169,
  • alkaline phosphatase, placental (Regan isozyme),
  • NM_001632,
  • uc002vsq.4,
  • HGNC:439,
  • ALP,
  • PLAP-1,
  • PLAP,
  • PALP,
  • PALP,
  • ALPP,
  • PLAP,
  • IAP
  • identifiers:
  • 250,
  • ENSG00000163283,
  • ALPP

Genome feature

Region: gene ? Length: 4139  
Location: 2:232378751-232382889 Cyto location: 2q37.1

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3 SN Ps

5 Cross References

17 Data Sets

21 Homologues

0 Located Features

97 Rna Seq Results