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Gene : GABRA4 Homo sapiens

Name  ? gamma-aminobutyric acid type A receptor subunit alpha4 Cytological Location  4p12
Brief Description  gamma-aminobutyric acid type A receptor subunit alpha4
Description  Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1). Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011]
  • synonyms:
  • GABRA4,
  • uc003gxg.3,
  • NM_000809,
  • HGNC:4078,
  • GABA(A) receptor, alpha 4,
  • gamma-aminobutyric acid (GABA) A receptor, alpha 4,
  • OTTHUMG00000099431
  • identifiers:
  • 2557,
  • ENSG00000109158,
  • GABRA4

Genome feature

Region: gene ? Length: 74682  
Location: 4:46918900-46993581 reverse strand Cyto location: 4p12

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526 SN Ps

5 Cross References

17 Data Sets

7 Homologues

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97 Rna Seq Results