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Gene : FBXO7 Homo sapiens

Name  ? F-box protein 7 Cytological Location  22q12.3
Brief Description  F-box protein 7
Description  This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined. [provided by RefSeq, Jul 2008]
  • synonyms:
  • NM_001033024,
  • uc003amq.4,
  • PARK15,
  • HGNC:13586,
  • FBX07,
  • AF129537,
  • FBX7,
  • FBX7,
  • OTTHUMG00000030674,
  • F-box only protein 7,
  • FBXO7,
  • Fbx,
  • PARK15,
  • PKPS,
  • FBX
  • identifiers:
  • 25793,
  • ENSG00000100225,
  • FBXO7

Genome feature

Region: gene ? Length: 24150  
Location: 22:32474682-32498831 Cyto location: 22q12.3


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

Gene --> Proteins.

SNPs

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Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

3753 SN Ps

5 Cross References

19 Data Sets

3 Homologues

0 Located Features

97 Rna Seq Results