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Gene : GAK Homo sapiens

Name  ? cyclin G associated kinase Cytological Location  4p16.3
Brief Description  cyclin G associated kinase
Description  In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
  • synonyms:
  • DNAJ26,
  • GAK,
  • DNAJC26,
  • OTTHUMG00000088301,
  • D88435,
  • uc003gbm.6,
  • DNAJC26,
  • HGNC:4113,
  • NM_005255,
  • auxilin-2
  • identifiers:
  • 2580,
  • ENSG00000178950,
  • GAK

Genome feature

Region: gene ? Length: 83055  
Location: 4:849276-932330 reverse strand Cyto location: 4p16.3


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Proteins

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SNPs

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Disease

0 Diseases

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Expression

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3740 SNPs

5 Cross References

17 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results