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Gene : CHTOP Homo sapiens

Name  ? chromatin target of PRMT1 Cytological Location  1q21.3
Brief Description  chromatin target of PRMT1
Description  This gene encodes a small nuclear protein that is characterized by an arginine and glycine rich region. This protein may have an important role in the regulation of fetal globin gene expression and in the activation of estrogen-responsive genes. A recent study reported that this protein binds 5-hydroxymethylcytosine (5hmC) and associates with an arginine methyltransferase complex (methylosome), which promotes methylation of arginine 3 of histone H4 (H4R3) and activation of genes involved in glioblastomagenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2015]
  • synonyms:
  • C1orf77,
  • SRAG-5,
  • Friend of Prmt1,
  • SRAG,
  • pp7704,
  • HGNC:24511,
  • FL-SRAG,
  • SRAG,
  • CHTOP,
  • small protein rich in arginine and glycine,
  • FOP,
  • SRAG-3,
  • C10orf77,
  • OTTHUMG00000037052,
  • DKFZP547E1010,
  • C1orf77,
  • uc001fcm.3,
  • chromosome 1 open reading frame 77,
  • FOP,
  • NM_015607
  • identifiers:
  • 26097,
  • ENSG00000160679,

Genome feature

Region: gene ? Length: 12241  
Location: 1:153634066-153646306 Cyto location: 1q21.3

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3740 SNPs

5 Cross References

15 Data Sets

11 Homologues

0 Located Features

97 Rna Seq Results