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Gene : FBXO2 Homo sapiens

Name  ? F-box protein 2 Cytological Location  1p36.22
Brief Description  F-box protein 2
Description  This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state. [provided by RefSeq, Jul 2008]
  • synonyms:
  • F-box only protein 2,
  • FBX2,
  • Fbs1,
  • organ of Corti protein 1,
  • Nfb42,
  • FBG1,
  • AF174594,
  • OTTHUMG00000002072,
  • OCP1,
  • NFB42,
  • NM_012168,
  • HGNC:13581,
  • FBXO2,
  • uc001asj.4,
  • OCP1,
  • Fbs1,
  • Fbg1,
  • FBX2
  • identifiers:
  • 26232,
  • ENSG00000116661,
  • FBXO2

Genome feature

Region: gene ? Length: 6043  
Location: 1:11648387-11654429 reverse strand Cyto location: 1p36.22


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Disease

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Expression

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Other

392 SN Ps

5 Cross References

16 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results