help  | about  | cite  | software

Gene : ARFGAP3 Homo sapiens

Name  ? ADP ribosylation factor GTPase activating protein 3 Cytological Location  22q13.2
Brief Description  ADP ribosylation factor GTPase activating protein 3
Description  The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene. [provided by RefSeq, Nov 2008]
  • synonyms:
  • ADP-ribosylation factor GTPase activating protein 1,
  • HGNC:661,
  • ARFGAP3,
  • OTTHUMG00000150718,
  • AK002083,
  • ARFGAP1,
  • NM_014570,
  • uc003bdd.3,
  • identifiers:
  • 26286,
  • ENSG00000242247,

Genome feature

Region: gene ? Length: 60793  
Location: 22:42796502-42857294 reverse strand Cyto location: 22q13.2

Uni Prot Comments Displayer

Protein Atlas Displayer

Gene Expression Atlas Tissues Displayer

Gene Expression Atlas Diseases Displayer

Publication Counts Displayer

Curated Proteins Displayer


Gene Ontology Displayer

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


J Browse Displayer

Gene Structure Displayer

Overlapping Features Displayer

Mouse Alleles Displayer

Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


Homologue Displayer


Cytoscape Network Displayer

Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3740 SN Ps

5 Cross References

15 Data Sets

6 Homologues

0 Located Features

97 Rna Seq Results