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Gene : GCKR Homo sapiens

Name  ? glucokinase regulator Cytological Location  2p23.3
Brief Description  glucokinase regulator
Description  This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008]
  • synonyms:
  • glucokinase (hexokinase 4) regulatory protein,
  • NM_001486,
  • uc002rky.4,
  • Z48475,
  • FGQTL5,
  • OTTHUMG00000128426,
  • hexokinase 4 regulator,
  • GKRP,
  • GCKR,
  • HGNC:4196
  • identifiers:
  • 2646,
  • ENSG00000084734,
  • GCKR

Genome feature

Region: gene ? Length: 26851  
Location: 2:27496839-27523689 Cyto location: 2p23.3


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

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Genomics

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Proteins

Gene --> Proteins.

SNPs

Gene Report --> GWAS hit

Disease

1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

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Gene Ontology

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Other

552 SN Ps

5 Cross References

18 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results