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Gene : GDF10 Homo sapiens

Name  ? growth differentiation factor 10 Cytological Location  10q11.22
Brief Description  growth differentiation factor 10
Description  This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. Additionally, this protein may act as a tumor suppressor and reduced expression of this gene is associated with oral cancer. [provided by RefSeq, Jul 2016]
  • synonyms:
  • NM_004962,
  • BMP3B,
  • HGNC:4215,
  • BMP-3b,
  • BMP-3b,
  • BIP,
  • GDF10,
  • OTTHUMG00000188319,
  • uc001jfb.4,
  • L42113
  • identifiers:
  • 2662,
  • ENSG00000266524,
  • GDF10

Genome feature

Region: gene ? Length: 13381  
Location: 10:47300197-47313577 Cyto location: 10q11.22

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

137 SN Ps

5 Cross References

16 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results