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Gene : GH1 Homo sapiens

Name  ? growth hormone 1 Cytological Location  17q23.3
Brief Description  growth hormone 1
Description  The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq, Jul 2008]
  • synonyms:
  • OTTHUMG00000172293,
  • IGHD1A,
  • GH-N,
  • hGH-N,
  • pituitary growth hormone,
  • NM_000515,
  • somatotropin,
  • GHN,
  • hGH-N,
  • GH-N,
  • GHB5,
  • M13438,
  • uc002jdj.4,
  • GH1,
  • IGHD2,
  • HGNC:4261,
  • IGHD1B,
  • GH,
  • GH,
  • GHN
  • identifiers:
  • 2688,
  • ENSG00000259384,
  • GH1

Genome feature

Region: gene ? Length: 1637  
Location: 17:63917203-63918839 reverse strand Cyto location: 17q23.3

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4 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

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5 SN Ps

5 Cross References

18 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results