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Gene : GH2 Homo sapiens

Name  ? growth hormone 2 Cytological Location  17q23.3
Brief Description  growth hormone 2
Description  The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. As in the case of its pituitary counterpart, growth hormone 1, the predominant isoform of this particular family member shows similar somatogenic activity, with reduced lactogenic activity. Mutations in this gene lead to placental growth hormone/lactogen deficiency. [provided by RefSeq, Jul 2008]
  • synonyms:
  • placenta-specific growth hormone,
  • GHV,
  • HGNC:4262,
  • GHB2,
  • J03756,
  • GH2,
  • GHL,
  • placental-specific growth hormone,
  • GHV,
  • GH-V,
  • GHL,
  • GH-V,
  • NM_002059,
  • OTTHUMG00000172284,
  • uc002jco.3,
  • hGH-V,
  • hGH-V
  • identifiers:
  • 2689,
  • ENSG00000136487,
  • GH2

Genome feature

Region: gene ? Length: 1730  
Location: 17:63880215-63881944 reverse strand Cyto location: 17q23.3


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Disease

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Expression

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Other

23 SN Ps

5 Cross References

16 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results