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Gene : DKK3 Homo sapiens

Name  ? dickkopf WNT signaling pathway inhibitor 3 Cytological Location  11p15.3
Brief Description  dickkopf WNT signaling pathway inhibitor 3
Description  This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
  • synonyms:
  • dickkopf 3 homolog (Xenopus laevis),
  • NM_013253,
  • RIG,
  • RIG,
  • HGNC:2893,
  • uc001mjw.4,
  • regulated in glioma,
  • REIC,
  • OTTHUMG00000165709,
  • REIC,
  • AF177396,
  • DKK3,
  • dickkopf (Xenopus laevis) homolog 3
  • identifiers:
  • 27122,
  • ENSG00000050165,
  • DKK3

Genome feature

Region: gene ? Length: 46849  
Location: 11:11962979-12009827 reverse strand Cyto location: 11p15.3

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0 Pathways

Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

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Gene --> Proteins.


Gene Report --> GWAS hit


0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



0 Pathways

3753 SN Ps

5 Cross References

17 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results