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Gene : AFF4 Homo sapiens

Name  ? AF4/FMR2 family member 4 Cytological Location  5q31.1
Brief Description  AF4/FMR2 family member 4
Description  The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23). [provided by RefSeq, Oct 2011]
  • synonyms:
  • OTTHUMG00000059838,
  • ALL1 fused gene from 5q31,
  • NM_014423,
  • MCEF,
  • AF5Q31,
  • MCEF,
  • CHOPS,
  • uc003kyd.4,
  • AFF4,
  • AF4/FMR2 family, member 4,
  • AF5Q31,
  • HGNC:17869,
  • AF197927
  • identifiers:
  • 27125,
  • ENSG00000072364,
  • AFF4

Genome feature

Region: gene ? Length: 88275  
Location: 5:132875381-132963655 reverse strand Cyto location: 5q31.1

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

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Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3740 SN Ps

5 Cross References

19 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results