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Gene : C5AR2 Homo sapiens

Name  ? complement component 5a receptor 2 Cytological Location  19q13.32
Brief Description  complement component 5a receptor 2
Description  This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
  • synonyms:
  • uc010ela.2,
  • OTTHUMG00000183505,
  • C5AR2,
  • GPR77,
  • C5L2,
  • C5L2,
  • AB038237,
  • GPF77,
  • HGNC:4527,
  • GPR77,
  • NM_018485,
  • G protein-coupled receptor 77
  • identifiers:
  • 27202,
  • ENSG00000134830,
  • C5AR2

Genome feature

Region: gene ? Length: 15716  
Location: 19:47331614-47347329 Cyto location: 19q13.32

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0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



189 SN Ps

5 Cross References

16 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results