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Gene : BMP10 Homo sapiens

Name  ? bone morphogenetic protein 10 Cytological Location  2p13.3
Brief Description  bone morphogenetic protein 10
Description  This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation. [provided by RefSeq, Aug 2016]
  • synonyms:
  • NM_014482,
  • AF101441,
  • BMP10,
  • HGNC:20869,
  • OTTHUMG00000129573,
  • uc002sez.1
  • identifiers:
  • 27302,
  • ENSG00000163217,
  • BMP10

Genome feature

Region: gene ? Length: 10489  
Location: 2:68860909-68871397 reverse strand Cyto location: 2p13.3


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Function

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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Genomics

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Proteins

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SNPs

Gene Report --> GWAS hit

Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

Homology

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Interactions

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Expression

Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

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Other

0 SN Ps

5 Cross References

13 Data Sets

40 Homologues

0 Located Features

97 Rna Seq Results