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Gene : GLDC Homo sapiens

Name  ? glycine decarboxylase Cytological Location  9p24.1
Brief Description  glycine decarboxylase
Description  Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the P protein, which binds to glycine and enables the methylamine group from glycine to be transferred to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH).[provided by RefSeq, Jan 2010]
  • synonyms:
  • glycine dehydrogenase,
  • nonketotic hyperglycinemia,
  • glycine dehydrogenase (decarboxylating),
  • glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P),
  • D90239,
  • glycine cleavage system protein P,
  • GLDC,
  • HYGN1,
  • GCE,
  • GCSP,
  • NM_000170,
  • NKH,
  • HGNC:4313,
  • uc003zkc.4,
  • GCSP,
  • OTTHUMG00000019524
  • identifiers:
  • 2731,
  • ENSG00000178445,
  • GLDC

Genome feature

Region: gene ? Length: 113263  
Location: 9:6532467-6645729 reverse strand Cyto location: 9p24.1


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Disease

1 Diseases

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3753 SN Ps

5 Cross References

20 Data Sets

5 Homologues

0 Located Features

97 Rna Seq Results