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Gene : GNA11 Homo sapiens

Name  ? G protein subunit alpha 11 Cytological Location  19p13.3
Brief Description  G protein subunit alpha 11
Description  The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations. [provided by RefSeq, Dec 2013]
  • synonyms:
  • uc010xhe.5,
  • FBH2,
  • FBH2,
  • FBH,
  • FHH2,
  • hypocalciuric hypercalcemia 2,
  • HHC2,
  • guanine nucleotide binding protein (G protein), alpha 11 (Gq class),
  • HHC2,
  • HGNC:4379,
  • OTTHUMG00000180631,
  • HYPOC2,
  • NM_002067,
  • AF493900,
  • GNA-11,
  • GNA11,
  • FBH,
  • FHH2
  • identifiers:
  • 2767,
  • ENSG00000088256,
  • GNA11

Genome feature

Region: gene ? Length: 29638  
Location: 19:3094362-3123999 Cyto location: 19p13.3


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Disease

2 Diseases

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212 SN Ps

5 Cross References

20 Data Sets

11 Homologues

0 Located Features

97 Rna Seq Results