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Gene : GNRH1 Homo sapiens

Name  ? gonadotropin releasing hormone 1 Cytological Location  8p21.2
Brief Description  gonadotropin releasing hormone 1
Description  This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism. [provided by RefSeq, Nov 2015]
  • synonyms:
  • GRH,
  • X01059,
  • GNRH1,
  • LNRH,
  • LHRH,
  • NM_001083111,
  • GNRH,
  • GNRH,
  • HGNC:4419,
  • GRH,
  • progonadoliberin-1,
  • OTTHUMG00000163852,
  • uc064lhq.1,
  • LHRH,
  • leuteinizing-releasing hormone
  • identifiers:
  • 2796,
  • ENSG00000147437,
  • GNRH1

Genome feature

Region: gene ? Length: 5783  
Location: 8:25419258-25425040 reverse strand Cyto location: 8p21.2


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Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Proteins

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SNPs

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Disease

2 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]

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Expression

Gene(s) --> Significant SNPs (GTex data)

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Other

202 SN Ps

5 Cross References

20 Data Sets

2 Homologues

0 Located Features

97 Rna Seq Results