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Gene : GOT2 Homo sapiens

Name  ? glutamic-oxaloacetic transaminase 2 Cytological Location  16q21
Brief Description  glutamic-oxaloacetic transaminase 2
Description  Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
  • synonyms:
  • KYAT4,
  • uc002eof.2,
  • HGNC:4433,
  • GOT2,
  • OTTHUMG00000133769,
  • aspartate transaminase 2,
  • mitAAT,
  • glutamic-oxaloacetic transaminase 2, mitochondrial,
  • glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2),
  • KATIV,
  • kynurenine aminotransferase IV,
  • KATIV,
  • NM_002080,
  • KAT4,
  • aspartate aminotransferase 2,
  • KAT4,
  • KYAT4,
  • mitAAT
  • identifiers:
  • 2806,
  • ENSG00000125166,
  • GOT2

Genome feature

Region: gene ? Length: 27186  
Location: 16:58707131-58734316 reverse strand Cyto location: 16q21

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Gene --> GO terms.

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Chromosomal location.

Gene --> GO terms.

Gene --> Overlapping genes.


Gene --> Proteins.


Gene Report --> GWAS hit


1 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

Gene --> Alleles and Disease (clinVar data)

Gene -> HPO annotation (Human Phenotype Ontology)

Mouse Gene --> Allele [Phenotype]


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Gene --> Physical and Genetic Interactions


Gene(s) --> Significant SNPs (GTex data)

Gene Ontology

Gene --> GO terms.



3753 SN Ps

5 Cross References

19 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results