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Gene : GP5 Homo sapiens

Name  ? glycoprotein V platelet Cytological Location  3q29
Brief Description  glycoprotein V platelet
Description  Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al., 1998 [PubMed 9616133]).[supplied by OMIM, Nov 2010]
  • synonyms:
  • CD42d,
  • uc062rou.1,
  • GP5,
  • OTTHUMG00000150345,
  • GPV,
  • NM_004488,
  • CD42d,
  • HGNC:4443,
  • glycoprotein V (platelet),
  • platelet glycoprotein V,
  • L11238
  • identifiers:
  • 2814,
  • ENSG00000178732,
  • GP5

Genome feature

Region: gene ? Length: 4446  
Location: 3:194394821-194399266 reverse strand Cyto location: 3q29


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347 SN Ps

5 Cross References

16 Data Sets

8 Homologues

0 Located Features

97 Rna Seq Results