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Gene : CCR10 Homo sapiens

Name  ? C-C motif chemokine receptor 10 Cytological Location  17q21.2
Brief Description  C-C motif chemokine receptor 10
Description  Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]
  • synonyms:
  • GPR2,
  • AF215981,
  • G protein-coupled receptor 2,
  • NM_016602,
  • chemokine (C-C motif) receptor 10,
  • HGNC:4474,
  • GPR2,
  • CCR10,
  • OTTHUMG00000132301,
  • uc002iax.5
  • identifiers:
  • 2826,
  • ENSG00000184451,
  • CCR10

Genome feature

Region: gene ? Length: 2955  
Location: 17:42678889-42681843 reverse strand Cyto location: 17q21.2


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Proteins

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SNPs

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Disease

0 Diseases

Gene (Hum OR Rat) --> Mouse Allele (Phenotype)

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Expression

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Other

88 SN Ps

5 Cross References

17 Data Sets

4 Homologues

0 Located Features

97 Rna Seq Results